Preheat your oven to 350 degrees F. This is an important step as it ensures your meatloaf cooks evenly and thoroughly. Line a baking sheet with foil and coat it with non-stick spray, then set it aside.
In a large bowl, combine the 2 lbs. lean ground beef, 1 cup Italian breadcrumbs, 2 eggs, ½ cup onion, diced, 2 tsp garlic powder, 2 tsp chopped parsley, 1 tsp salt, and 1 tsp pepper. Use clean hands to mix the ingredients until they are fully combined. It’s important to handle the mixture gently, so it doesn’t become tough.
Press the meatloaf mixture into a loaf shape, about 8 inches by 4 inches, on the prepared baking sheet. Make sure to create an even surface, which will help the meatloaf cook evenly.
Bake the meatloaf in the preheated oven for 45 minutes. This initial baking time allows it to set and cook through.
After 45 minutes, remove the meatloaf from the oven and increase the temperature to 400 degrees. This step helps to create a nice crust on the outside.
In a small bowl, whisk together the ½ cup BBQ sauce, ⅓ cup ketchup, 2 tbsp brown sugar, and 1 tsp yellow mustard for the topping. This mixture will add a delicious glaze that enhances the meatloaf's flavor.
Spread the topping evenly over the meatloaf, ensuring it’s well covered. This will create a beautiful, caramelized layer as it bakes.
Return the meatloaf to the oven and bake for an additional 10 to 15 minutes, until the internal temperature reaches 160 degrees in the center. Use a meat thermometer for accuracy!
Once done, let the meatloaf rest for about 5 to 10 minutes before slicing. This resting time allows the juices to redistribute, ensuring each slice is moist and flavorful. Enjoy your lovely meal!